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J Biol Chem 246:402411 Shug AL, Shrago E, Bittar N, Folts JD, Koke JR (1975) Acyl-CoA inhibition of adenine nucleotide translocation in ischemic myocardium

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Taken together with the findings that utilization of esketamine as an antidepressant increases LAC levels [59], the fact that the decrease in LAC levels in subjects with MDD is independent of psychotropic drug treatment raises the possibility that increasing LAC levels may be needed to induce antidepressant effects